Author

M. Valero

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

C. Destombe· 2 shared L. Fouqueau· 2 shared L. Reynes· 2 shared S. Mauger· 2 shared A. Blanfune-Thibaut· 1 shared A. F. Peters· 1 shared B. Liu· 1 shared C. A. Dreiss· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersEvolutionary Biology

C. Destombe

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Author profile →

4 papers

Recent·Most cited

Temporal genomics help in deciphering neutral and adaptive patterns in the contemporary evolution of kelp populations

L. Reynes, L. Fouqueau, D. Aurelle, S. Mauger, C. Destombe, M. Valero

This study uses temporal genomics to analyze adaptive and neutral genetic patterns in kelp populations, identifying temperature-driven adaptation and contrasting evolutionary scenarios across populations.

bioRxiv · May 22, 2023Evolutionary Biology

Influence of oceanography and geographic distance on genetic structure: how varying the sampled domain influences conclusions in Laminaria digitata

L. Fouqueau, L. Reynes, F. Tempera, T. Bajjouk, A. Blanfune-Thibaut, C. Chevalier, M. Laurans, S. Mauger, M. Sourisseau, J. Assis, L. Leveque, M. Valero

This study evaluates how sampling domain variation affects genetic structure conclusions in Laminaria digitata by analyzing microsatellite data from 32 populations.

bioRxiv · May 11, 2023 · PreprintEvolutionary Biology

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.

L. Sanderson, M. da Silva, G. N. Sekhar, R. C. Brown, H. Burrell-Saward, M. Fidanboylu, B. Liu, L. A. Dailey, C. A. Dreiss, C. Lorenz, M. Christie, S. Persaud, V. Yardley, S. L. Croft, M. Valero, S. A. Thomas

This paper develops an intravenous pentamidine formulation using Pluronic micelles to enhance CNS exposure for stage 2 HAT treatment, finding no major neurotoxicity but limited BBB penetration enhancement.

bioRxiv · Apr 18, 2019Pharmacology & Toxicology

Evolution of life cycles and reproductive traits: insights from the brown algae

S. Heesch, M. Serrano-Serrano, R. Luthringer, A. F. Peters, C. Destombe, J. M. Cock, M. Valero, D. Roze, N. Salamin, s. m. coelho

This study examines the evolution of life cycle and reproductive traits in brown algae, finding diploid growth may evolve due to mutation complementation and haploid sex determination is ancestral.

bioRxiv · Feb 5, 2019Evolutionary Biology