Author

C. A. Dreiss

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

B. Liu· 1 shared C. D. Lorenz· 1 shared C. Lorenz· 1 shared D. Danovi· 1 shared D. Hoogland· 1 shared D. Marciano· 1 shared E. Gentleman· 1 shared E. Hamrud· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPharmacology & Toxicology

B. Liu

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Author profile →

2 papers

Recent·Most cited

ILC1-derived TGFβ1 drives intestinal remodelling

G. M. Jowett, M. D. A. Norman, T. T. L. Yu, P. Rosell Arevalo, D. Hoogland, S. Lust, E. Read, E. Hamrud, N. J. Walters, U. Niazi, M. W. H. Chung, D. Marciano, O. S. Omer, T. Zabinski, D. Danovi, , E. Gentleman

The paper shows ILC1-derived TGFβ1 drives intestinal epithelial crypt expansion and extracellular matrix remodeling in co-cultured organoids.

bioRxiv · Apr 20, 2020Immunology

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.

L. Sanderson, M. da Silva, G. N. Sekhar, R. C. Brown, H. Burrell-Saward, M. Fidanboylu, B. Liu, L. A. Dailey, C. A. Dreiss, C. Lorenz, M. Christie, S. Persaud, V. Yardley, S. L. Croft, M. Valero, S. A. Thomas

This paper develops an intravenous pentamidine formulation using Pluronic micelles to enhance CNS exposure for stage 2 HAT treatment, finding no major neurotoxicity but limited BBB penetration enhancement.

bioRxiv · Apr 18, 2019Pharmacology & Toxicology