The Hsp70/Hsp90 Co-Chaperone Hop/Stip1 Shifts the Proteostatic Balance from Folding Towards Degradation
K. Bhattacharya, L. Weidenauer, T. Moran Luengo, P. C. Echeverria, L. Bernasconi, D. Wider, M. Villemin, C. Bauer, S. G. D. Rüdiger, M. Quadroni, D. Picard
This study shows that Hop/Stip1 regulates proteostasis by shifting the balance between protein folding and degradation in eukaryotes.
bioRxiv · Feb 27, 2019Cell Biology