Author

L. Bernasconi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Picard· 2 shared D. Wider· 2 shared K. Bhattacharya· 2 shared A. Addetia· 1 shared A. Ceschi· 1 shared A. Franzetti-Pellanda· 1 shared A. Rajesh· 1 shared B. Guarino· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

D. Picard

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Hsf1 and the molecular chaperone Hsp90 support a "rewiring stress response" leading to an adaptive cell size increase in chronic stress

S. Maiti, K. Bhattacharya, D. Wider, D. Hany, O. Panasenko, L. Bernasconi, N. Hulo, D. Picard

The paper shows that chronic mild stress leads to adaptive cell size increase through Hsf1 and Hsp90, enhancing resilience to persistent stress.

bioRxiv · Jan 25, 2023Cell Biology

Therapeutic and vaccine-induced cross-reactive antibodies with effector function against emerging Omicron variants

A. Addetia, L. Piccoli, J. B. Case, Y.-J. Park, M. Beltramello, B. Guarino, H. Dang, D. Pinto, S. Scheaffer, K. Sprouse, J. Bassi, C. Silacci-Fregni, F. Muoio, M. Dini, L. Vincenzetti, , Fran

The paper shows that cross-reactive antibodies, like S309, retain effector functions against emerging Omicron variants despite reduced neutralization.

bioRxiv · Jan 17, 2023 · PreprintImmunology

The Hsp70/Hsp90 Co-Chaperone Hop/Stip1 Shifts the Proteostatic Balance from Folding Towards Degradation

K. Bhattacharya, L. Weidenauer, T. Moran Luengo, P. C. Echeverria, L. Bernasconi, D. Wider, M. Villemin, C. Bauer, S. G. D. Rüdiger, M. Quadroni, D. Picard

This study shows that Hop/Stip1 regulates proteostasis by shifting the balance between protein folding and degradation in eukaryotes.

bioRxiv · Feb 27, 2019Cell Biology