Author

P. C. Echeverria

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Organism:yeast· 1

Frequent Co-Authors

D. Picard· 2 shared K. Bhattacharya· 2 shared A. Joshi· 1 shared C. Bauer· 1 shared D. Wider· 1 shared L. Bernasconi· 1 shared L. Weidenauer· 1 shared M. Quadroni· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

D. Picard

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Author profile →

2 papers

Recent·Most cited

The Hsp70/Hsp90 Co-Chaperone Hop/Stip1 Shifts the Proteostatic Balance from Folding Towards Degradation

K. Bhattacharya, L. Weidenauer, T. Moran Luengo, P. C. Echeverria, L. Bernasconi, D. Wider, M. Villemin, C. Bauer, S. G. D. Rüdiger, M. Quadroni, D. Picard

This study shows that Hop/Stip1 regulates proteostasis by shifting the balance between protein folding and degradation in eukaryotes.

bioRxiv · Feb 27, 2019Cell Biology

The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity

P. C. Echeverria, K. Bhattacharya, A. Joshi, T. Wang, D. Picard

This study shows that cancer cells are hypersensitive to Hsp90 inhibitors due to a shift in cellular quiescence and activity balance, which can be modulated by growth factors and proteostasis challenges.

bioRxiv · Nov 16, 2018Cancer Biology