M. Watt

Disrupting the interaction between AMBRA1 and DLC1 is a promising therapeutic strategy for neurodegeneration that prevents apoptosis while enhancing autophagy and mitophagy

The paper investigates AMBRA1 mutants to identify strategies that prevent apoptosis and enhance autophagy/mitophagy in neurodegeneration, finding that AMBRA1TAT, which disrupts DLC1 interaction, shows the most promise.

Spatially distinct phytohormone responses of individual Arabidopsis thaliana root cells to infection and colonization by Fusarium oxysporum

This study shows that SA, JA, and ET act in distinct spatial zones in Arabidopsis root cells during infection by Fusarium oxysporum, with SA inducing cell death and JA initiating defense.

pGG-PIP: A GreenGate (GG) entry vector collection with Plant Immune system Promoters (PIP)

The paper introduces pGG-PIP, a collection of GreenGate vectors with plant immune system promoters, enabling rapid construction of expression vectors for studying plant immunity.

Variation in root system architecture among the founder parents of two 8-way MAGIC wheat populations for selection in breeding

The paper evaluates root system architecture variation in two MAGIC wheat populations to identify traits with high heritability for breeding improvement.

Transcriptional regulation of ZIP genes is independent of local zinc status in Brachypodium shoots upon zinc deficiency and resupply

The paper investigates zinc homeostasis in Brachypodium by analyzing gene expression and ionomic changes under zinc deficiency and resupply, identifying root-to-shoot signaling mechanisms.

Resolution of the proteome, transcript and ionome dynamics upon Zn re-supply in Zn-deficient Arabidopsis

This study examines the dynamic changes in proteome, transcriptome, and ionome of Zn-deficient Arabidopsis after Zn re-supply, revealing rapid Zn uptake and regulatory responses.

Multi-lab EcoFAB study shows highly reproducible physiology and depletion of soil metabolites by a model grass

The paper shows that Brachypodium distachyon consistently responds to soil conditions across labs, depleting soil metabolites and altering root morphology.