Myofibrillar malformations that arise in mdx muscle fibers are driven by detyrosinated microtubules
A. Harriot, T. Altair-Morris, C. Venegas, J. Kallenbach, K. Pinto, H. Joca, M.-J. Moutin, G. Shi, J. Ursitti, A. Grosberg, C. Ward
This study identifies detyrosinated microtubules as a driver of myofibrillar malformations in dystrophic skeletal muscle fibers, linking increased deTyr-MT levels to structural impairments.
bioRxiv · Mar 27, 2023 · PreprintPathology