Author

E. Denarier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Andrieux· 2 shared B. Blot· 2 shared I. Arnal· 2 shared S. Ramirez-Rios· 2 shared A. Akhmanova· 1 shared A. Favier· 1 shared A. Rai· 1 shared A. Vernet· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

A. Andrieux

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Huntingtin bundles and changes the local proteome of actin filaments in neurons

R. Carpentier, M. Capizzi, H. Kim, J. Novion-Ducassou, E. Denarier, B. Blot, Y. Coute, I. Arnal, J.-J. Song, S. Humbert

This study shows that Huntingtin (HTT) binds to F-actin, bundles actin filaments, and modulates the association of Drebrin1 with actin, affecting axonal growth and cytoskeletal organization in neurons.

bioRxiv · Aug 29, 2023Cell Biology

VASH1-SVBP and VASH2-SVBP generate different detyrosination profiles on microtubules

S. Ramirez-Rios, S. R. Choi, C. Sanyal, T. Blum, C. Bosc, F. Krichen, E. Denarier, J.-M. Soleilhac, B. Blot, C. Janke, V. Stoppin-Mellet, M. M. Magiera, I. Arnal, M. O. Steinmetz, M.-J. Moutin

This paper shows VASH1-SVBP and VASH2-SVBP generate distinct detyrosination patterns on microtubules through different molecular mechanisms.

bioRxiv · Jun 2, 2022Cell Biology

Modeling disease-correlated TUBA1A mutation in budding yeast reveals a molecular basis for tubulin dysfunction

E. Denarier, K. H. Ecklund, G. Berthier, A. Favier, S. Gory, L. De Macedo, C. Delphin, A. Andrieux, S. M. Markus, C. Boscheron

This study models a TUBA1A mutation in budding yeast to reveal how it disrupts microtubule function and dynein regulation, leading to spindle positioning defects.

bioRxiv · Apr 13, 2020 · PreprintCell Biology

Two antagonistic microtubule targeting drugs act synergistically to kill cancer cells

L. Peronne, E. Denarier, A. Rai, R. Prudent, A. Vernet, P. Suzanne, S. Ramirez-Rios, S. Michallet, M. Guidetti, J. Vollaire, D. Lucena-Agell, A.-S. Ribba, V. Josserand, J.-L. Coll, P. Dallemagne, , L. Lafanechere

The paper identifies Carba1, a microtubule-destabilizing drug, which synergizes with paclitaxel to enhance cancer cell killing in vitro and in vivo.

bioRxiv · Feb 6, 2020Cancer Biology