Author

M.-L. Nan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

C. Gao· 2 shared J. Zhang· 2 shared L. Han· 2 shared M.-W. Zhuang· 2 shared P.-H. Wang· 2 shared Y. Zheng· 2 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

C. Gao

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2 papers

Recent·Most cited

SARS-CoV-2 ORF9b Antagonizes Type I and III Interferons by Targeting Multiple Components of RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING Signaling Pathways

L. Han, M.-W. Zhuang, Y. Zheng, J. Zhang, M.-L. Nan, P.-H. Wang, C. Gao

This study identifies SARS-CoV-2 ORF9b as a viral protein that inhibits type I and III interferon responses by disrupting multiple innate antiviral signaling pathways.

bioRxiv · Aug 16, 2020Microbiology

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) Protein Inhibits Type I and III Interferon Production by Targeting RIG-I/MDA-5 Signaling

P.-H. Wang, Y. Zheng, M.-W. Zhuang, L. Han, J. Zhang, M.-L. Nan, C. Gao

This study identifies the SARS-CoV-2 M protein as an inhibitor of type I and III interferon production by disrupting RIG-I/MDA-5 signaling, thereby suppressing antiviral immunity and enhancing viral replication.

bioRxiv · Jul 26, 2020Immunology