Author

M.-W. Zhuang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Zhang· 3 shared P.-H. Wang· 3 shared C. Gao· 2 shared L. Han· 2 shared M.-L. Nan· 2 shared Y. Zheng· 2 shared D. Liu· 1 shared Q. Tang· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMicrobiology

J. Zhang

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3 papers

Recent·Most cited

SARS-CoV-2 ORF9b Antagonizes Type I and III Interferons by Targeting Multiple Components of RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING Signaling Pathways

L. Han, M.-W. Zhuang, Y. Zheng, J. Zhang, M.-L. Nan, P.-H. Wang, C. Gao

This study identifies SARS-CoV-2 ORF9b as a viral protein that inhibits type I and III interferon responses by disrupting multiple innate antiviral signaling pathways.

bioRxiv · Aug 16, 2020Microbiology

A Systemic and Molecular Study of Subcellular Localization of SARS-CoV-2 Proteins

J. Zhang, R. Cruz-cosme, M.-W. Zhuang, D. Liu, Y. Liu, S. Teng, P.-H. Wang, Q. Tang

This study characterizes the subcellular localization of SARS-CoV-2 proteins using expression in human cells and immunofluorescent assays, revealing their association with various organelles.

bioRxiv · Aug 2, 2020Microbiology

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) Protein Inhibits Type I and III Interferon Production by Targeting RIG-I/MDA-5 Signaling

P.-H. Wang, Y. Zheng, M.-W. Zhuang, L. Han, J. Zhang, M.-L. Nan, C. Gao

This study identifies the SARS-CoV-2 M protein as an inhibitor of type I and III interferon production by disrupting RIG-I/MDA-5 signaling, thereby suppressing antiviral immunity and enhancing viral replication.

bioRxiv · Jul 26, 2020Immunology