M.-Q. Zuo

D/E-rich peptides are less suitable than D/E-deficient peptides for identification by negative-ion HCD due to scarce production of sequencing ions from multiply charged precursors

The paper shows D/E-rich peptides produce fewer sequencing ions in negative-ion HCD MS, making them harder to identify, and suggests using proteases that generate D/E-deficient peptides for better results.

The acetyltransferase Eco1 elicits cohesin dimerization during S phase

This study shows that Eco1-mediated acetylation promotes cohesin dimerization during S phase, which is regulated by Hos1 and Wpl1.