NKX2.2 and KLF4 cooperate to regulate alpha cell identity
Elliott P. Brooks, McKenna R. Casey, Kristen L. Wells, Tsung-Yun Liu, Madeline Van Orman, Lori Sussel
This study identifies KLF4 as a novel factor that cooperates with NKX2.2 to regulate alpha cell identity by co-occupying promoters and modulating chromatin accessibility.
Genes & Development · Feb 1, 2025Peer-reviewedDevelopmental Biology