Allosteric factors in the calcium/calmodulin-responsive kinase II hub domain determine selectivity of GHB ligands for CaMKIIa
Stine Juul Gauger, Line B. Palmelund, Yongsong Tian, Aleš Marek, Mathias RJ Namini, Nane Griem‐Krey, Madeline Y. Petersen, Stefanie Kickinger, Jonas Sigurd Mortensen, Bente Frølund, Petrine Wellendorph
This study identifies allosteric factors in the CaMKII hub domain that determine GHB ligand selectivity for CaMKIIa over other isozymes.
Journal of Biological Chemistry · Apr 24, 2025Peer-reviewedBiochemistry