Coupling between acid-sensing ion channel 1a and the monocarboxylate transporter family shapes cellular pH response
Mette Homann Poulsen, Nadine Ritter, S. Maurya…·Stephan Alexander Pless
The paper identifies a functional interaction between ASIC1a and MCT1 that modulates proton sensitivity and desensitization, showing its role in glioblastoma cell survival and mouse lifespan.