Author

Madison Ahrens

Wayne State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Hyejeong JangiD· 1 shared Jing LiiD· 1 shared Katherine GurdzieliD· 1 shared Malathy P.V. ShekhariD· 1 shared Neeraja PurandareiD· 1 shared Pratima Nangia‐MakkeriD· 1 shared Seongho KimiD· 1 shared Siddhesh ArasiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Hyejeong JangORCID

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1 paper

Recent·Most cited

Relationship between melanoma vemurafenib tolerance thresholds and metabolic pathway choice and Wnt signaling involvement

Pratima Nangia‐Makker, Madison Ahrens, Neeraja Purandare, Siddhesh Aras, Jing Li, Katherine Gurdziel, Hyejeong Jang, Seongho Kim, Malathy P.V. Shekhar

This study identifies that vemurafenib resistance in BRAFV600E melanomas is linked to metabolic pathway choices and Wnt/β-catenin signaling, with varying tolerance thresholds affecting mitochondrial and pentose phosphate pathway utilization.

bioRxiv · Mar 6, 2025 · PreprintCancer Biology