Seongho Kim

This study identifies Polβ mutations that drive sensitivity to cisplatin and carboplatin in TNBC models, suggesting their use as predictive biomarkers for platinum-based therapies.

This paper develops a new compound KCI838 that selectively inhibits the AR-ELK1 axis in prostate cancer, showing potent anti-tumor activity in resistant models.

The paper shows rod photoreceptors control the dynamic switch of ON and OFF polarity in cone-signaling neurons through EAAT5 glutamate transporters.

This study investigates how canagliflozin affects brain aging and Alzheimer's-like pathology in mice, finding sex-specific effects on hippocampal function and disease markers.

This study identifies that vemurafenib resistance in BRAFV600E melanomas is linked to metabolic pathway choices and Wnt/β-catenin signaling, with varying tolerance thresholds affecting mitochondrial and pentose phosphate pathway utilization.

This study investigates the metabolic effects of low-dose benzene exposure in mice, finding mitochondrial dysfunction and dose-dependent changes in metabolic pathways.

This study identifies RCC1 as a novel therapeutic target in PDAC, showing its role in tumor progression and drug resistance through the c-Myc-RCC1-Ran axis.