Author

Pratima Nangia‐Makker

Wayne State UniversityORCID 0000-0002-1917-169XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Hyejeong JangiD· 1 shared Jing LiiD· 1 shared Katherine GurdzieliD· 1 shared Madison Ahrens· 1 shared Malathy P.V. ShekhariD· 1 shared Neeraja PurandareiD· 1 shared Seongho KimiD· 1 shared Siddhesh ArasiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Hyejeong JangORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMar 6, 2025

Relationship between melanoma vemurafenib tolerance thresholds and metabolic pathway choice and Wnt signaling involvement

Pratima Nangia‐Makker, Madison Ahrens, Neeraja Purandare…·Malathy P.V. Shekhar

This study identifies that vemurafenib resistance in BRAFV600E melanomas is linked to metabolic pathway choices and Wnt/β-catenin signaling, with varying tolerance thresholds affecting mitochondrial and pentose phosphate pathway utilization.

DOI 10.1101/2025.03.06.641924

humanmetabolomics

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