Phage detection by a bacterial NLR-related protein is mediated by DnaJ
Amy N. Conte, Madison E. Ruchel, Samantha M. Ridgeway, Emily M. Kibby, Toni A. Nagy, Aaron T. Whiteley
This study identifies DnaJ as essential for bNACHT25-mediated detection of RNA phages in E. coli, revealing a mechanism where phage coat protein activates the sensor without direct interaction.
PLoS Biology · May 30, 2025Peer-reviewedMicrobiology