Loss of coiled-coil protein Cep55 impairs abscission processes and results in p53-dependent apoptosis in developing cortex
Jessica Neville Little, Katrina C. McNeely, Nadine Michel, Christopher J. Bott, Kaela S. Lettieri, Madison R. Hecht, Sara A. Martin, Noelle D. Dwyer
This study shows that Cep55 loss in mice causes microcephaly through abscission defects and p53-dependent apoptosis in the developing cortex.
Journal of Neuroscience · Feb 23, 2021Peer-reviewedDevelopmental Biology