Christopher J. Bott

This paper identifies ORP3 as a lipid transfer protein that mediates lysosomal repair through interactions with LC3B and the TAK1-p38 signaling pathway.

This study shows that Cep55 loss in mice causes microcephaly through abscission defects and p53-dependent apoptosis in the developing cortex.

This study shows that nestin in immature neurons modulates cdk5 activity, affecting sensitivity to the guidance cue Sema3a, which influences axon growth cone morphology.