Off-target expression of Cre-dependent adeno-associated viruses in wild type C57BL/6J mice
Justin J. Botterill, Abdessattar Khlaifia, Brandon J. Walters, Mark A. Brimble, Helen E. Scharfman, Maithe Arruda-Carvalho
The paper investigates off-target expression of Cre-dependent AAVs in wild-type mice and finds extensive Cre-independent viral expression despite vendor, serotype, and promoter variations.
eNeuro · Nov 1, 2021Peer-reviewedNeuroscience