Author

Abdessattar Khlaifia

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:statistical model· 1

Frequent Co-Authors

Justin J. BotterilliD· 2 shared Maithé Arruda-CarvalhoiD· 2 shared A FontaineiD· 1 shared Alexander JordaniD· 1 shared Anna Elisabete Canella· 1 shared Anne‐Sophie RacineiD· 1 shared Arely Cruz-Sanchez· 1 shared Ashutosh V. PateliD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Justin J. BotterillORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dorsal peduncular cortex activity modulates affective behavior and fear extinction in mice

Justin J. Botterill, Abdessattar Khlaifia, Ryan Appings, Jennifer Wilkin, Francesca Violi, Hanista Premachandran, Arely Cruz-Sanchez, Anna Elisabete Canella, Ashutosh V. Patel, S. Danyal Zaidi, Maithé Arruda-Carvalho

This study shows that activating the dorsal peduncular cortex (DP/DTT) in mice increases anxiety-like behavior and affects fear extinction, suggesting a role in emotional regulation.

Neuropsychopharmacology · Jan 17, 2024Peer-reviewedNeuroscience

Maturation of Nucleus Accumbens Synaptic Transmission Signals a Critical Period for the Rescue of Social Deficits in a Mouse Model of Autism Spectrum Disorder

Melina Matthiesen, Abdessattar Khlaifia, Carl Frank David Steininger, Maryam Dadabhoy, Unza Mumtaz, Maithé Arruda-Carvalho

This study examines age-dependent changes in synaptic transmission in the nucleus accumbens of ASD mouse models and finds that early intervention with rapamycin rescues social deficits.

Molecular Brain · May 24, 2023Peer-reviewedNeuroscience

Off-target expression of Cre-dependent adeno-associated viruses in wild type C57BL/6J mice

Justin J. Botterill, Abdessattar Khlaifia, Brandon J. Walters, Mark A. Brimble, Helen E. Scharfman, Maithe Arruda-Carvalho

The paper investigates off-target expression of Cre-dependent AAVs in wild-type mice and finds extensive Cre-independent viral expression despite vendor, serotype, and promoter variations.

eNeuro · Nov 1, 2021Peer-reviewedNeuroscience

Regulation of hippocampal memory by mTORC1 in somatostatin interneuron

Julien Artinian, Alexander Jordan, Abdessattar Khlaifia, Ève Honoré, A Fontaine, Anne‐Sophie Racine, Isabel Laplante, Jean‐Claude Lacaille

This study shows that mTORC1 activity in somatostatin interneurons regulates hippocampal memory by modulating synaptic plasticity and fear memory consolidation.

Journal of Neuroscience · Sep 13, 2019Peer-reviewedNeuroscience