Evolutionary BiologybioRxiv
Positive selection on a regulatory insertion-deletion polymorphism in FADS2 influences apparent endogenous synthesis of arachidonic acid
Kumar S.D. Kothapalli, Kaixiong Ye, Maithili S. Gadgil…·J. Thomas Brenna
The paper identifies a regulatory insertion-deletion polymorphism in FADS2 associated with increased arachidonic acid synthesis in individuals with a plant-based diet.
DOI 10.1093/molbev/msw049