Author

Hui Gyu Park

The University of Texas at AustinORCID 0000-0002-0510-2095Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scATAC-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

J. Thomas Brenna· 2 shared James Thomas BrennaiD· 2 shared Paul D. SolowayiD· 2 shared Roman SpektoriD· 2 shared Abigail M. BenvieiD· 1 shared Alon KeinaniD· 1 shared Bethany P. CummingsiD· 1 shared Blaine A. HarlaniD· 1 shared

Activity by Year

2016-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

J. Thomas Brenna

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Author profile →

4 papers

Recent·Most cited

Ultra-high dose oral ω3 docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA) block tumorigenesis in a MYCN-driven neuroblastoma model

Vishwa Patel, Yan Ning Li, Lorraine-Rana E. Benhamou, Hui Gyu Park, Mariya Raleigh, James Thomas Brenna, John T. Powers

This paper shows that ultra-high dose omega-3 fatty acids block tumor formation in a neuroblastoma model, while omega-6 fatty acids promote it.

Cancers · Jan 23, 2025Peer-reviewedCancer Biology

Remodeling of gene regulatory networks underlying thermogenic stimuli-induced adipose beiging

Seo Yeon Lee, Abigail M. Benvie, Hui Gyu Park, Roman Spektor, Blaine A. Harlan, James Thomas Brenna, Daniel C. Berry, Paul D. Soloway

This study identifies common and distinct chromatin accessibility changes in adipose tissue from mice exposed to cold or Adrb3 agonists, revealing unique functional consequences of these stimuli on lipid composition and thermogenesis.

Communications Biology · Jun 14, 2022Peer-reviewedGenomics

Single-cell Chromatin Accessibility and Lipid Profiling Reveals a Metabolic Shift in Adipocytes Induced by Bariatric Surgery

Blaine Harlan, Hui Gyu Park, Roman Spektor, Bethany P. Cummings, J. Thomas Brenna, Paul D. Soloway

This study uses single-cell ATAC sequencing and lipid profiling to show that bariatric surgery alters chromatin accessibility and fatty acid profiles in adipose tissue, suggesting a metabolic shift mediated by Scd1.

PLoS ONE · Dec 31, 2021Peer-reviewedGenomics

Positive selection on a regulatory insertion-deletion polymorphism in FADS2 influences apparent endogenous synthesis of arachidonic acid

Kumar S.D. Kothapalli, Kaixiong Ye, Maithili S. Gadgil, Susan E. Carlson, Kimberly O. O'Brien, Ji Yao Zhang, Hui Gyu Park, Kinsley Ojukwu, James Zou, Stephanie S. Hyon, Kalpana S. Joshi, Alon Keinan, J. Thomas Brenna

The paper identifies a regulatory insertion-deletion polymorphism in FADS2 associated with increased arachidonic acid synthesis in individuals with a plant-based diet.

bioRxiv · Mar 6, 2016Evolutionary Biology