Genetic & Genomic MedicineHuman Genetics and Genomics AdvancesPeer-reviewed
A variance QTL approach to uncover gene-fish oil supplement interaction loci for 14 circulating unsaturated fatty acid traits
DOI 10.1016/j.xhgg.2026.100675
Author
Kaixiong Ye
University of GeorgiaORCID 0000-0003-4658-7292Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2016-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 15 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship5 shared papersGenetic & Genomic Medicine
Yitang SunORCID
Mutual co-authors in cluster
13 papers
Recent·Most cited
- GenomicsbioRxivPreprint
Assembly of a high-quality reference genome for the rat tapeworm Hymenolepis diminuta
Saurav Choudhary, Nikitha Sundaresha, Kaixiong Ye…·Tania Rozario
The paper presents a high-quality reference genome for Hymenolepis diminuta using PacBio HiFi long-read sequencing, achieving high contiguity and completeness.
DOI 10.64898/2026.06.23.734100 - Genetic & Genomic MedicineCurrent Developments in NutritionPeer-reviewed
Gene-diet interaction analysis in UK Biobank identified genetic loci that modify the association between fish oil supplementation and the incidence of dementia
Yueqi Lu, Huifang Xu, Yitang Sun…·Kaixiong Ye
The paper identifies 43 genetic loci that modify the effect of fish oil supplementation on dementia risk using UK Biobank data.
- Genetic & Genomic MedicineHuman Genetics and Genomics AdvancesPeer-reviewed
Genome-wide association studies and multi-omics integrative analysis reveal novel loci and their molecular mechanisms for circulating polyunsaturated, monounsaturated, and saturated fatty acids
Yitang Sun, Huifang Xu, Kaixiong Ye
The paper identifies novel genetic loci for circulating fatty acids and reveals their molecular mechanisms through GWAS and multi-omics integration.
7 citations - Genetic & Genomic MedicinemedRxivPreprint
A multi-level gene-diet interaction analysis of fish oil supplementation and 14 circulating polyunsaturated fatty acids-related traits identifies the FADS and GRP12 loci
Susan Adanna Ihejirika, Alexandra Huong Chiang, Aryaman Singh…·Kaixiong Ye
The paper identifies gene-diet interactions for fish oil supplementation and PUFA levels using GWIS in UK Biobank data, finding significant loci around FADS and GRP12.
DOI 10.1101/2024.12.12.24318956 - Cell BiologyFrontiers in Cell and Developmental BiologyPeer-reviewed
The main duct of von Ebner's glands is a source of Sox10+ taste bud progenitors and susceptible to pathogen infections
Wenxin Yu, Maria Eleni Kastriti, Mohamed Ishan…·Hong-Xiang Liu
- Genetic & Genomic MedicinemedRxivPreprint
Shared genetic basis informs the roles of polyunsaturated fatty acids in brain disorders
Huifang Xu, Yitang Sun, Michael Francis…·Kaixiong Ye
The paper examines the shared genetic basis between polyunsaturated fatty acids and brain disorders using genome-wide association data and identifies causal relationships and shared variants.
4 citations - Developmental BiologyScience AdvancesPeer-reviewed
Evolution of a chordate-specific mechanism for myoblast fusion
Haifeng Zhang, Renjie Shang, Kwantae Kim…·Pengpeng Bi
The paper investigates the evolutionary origins of myoblast fusion mechanisms in chordates, identifying the emergence of Myomaker and Myomixer and their roles in muscle development across species.
22 citations - Genetic & Genomic MedicineThe Journals of Gerontology Series APeer-reviewed
Altered blood cell traits underlie a major genetic locus of severe COVID-19
Jingqi Zhou, Yitang Sun, Weishan Huang, Kaixiong Ye
The paper identifies blood cell traits associated with the 3p21.31 genetic locus linked to severe COVID-19 and shows their connection to candidate gene expression.
14 citations - Genetic & Genomic MedicineNutrientsPeer-reviewed
The Causal Effects of Blood Iron and Copper on Lipid Metabolism Disease: Evidence from Phenome-wide Mendelian Randomization Study
Jingqi Zhou, Chang Liu, Michael Francis…·Kaixiong Ye
This study uses Mendelian randomization to show higher blood iron and copper levels are associated with lower risks of lipid metabolism disorders and related conditions.
35 citations - GenomicsGenome biologyPeer-reviewed
Admixture-enabled selection for rapid adaptive evolution in the Americas
Emily T. Norris, Lavanya Rishishwar, Aroon T. Chande…·I. King Jordan
The paper identifies admixture-enabled selection in Latin American populations, finding evidence of African ancestry enrichment at immune-related loci and polygenic selection for traits related to immunity and inflammation.
44 citationstop 4% - GenomicsNature Ecology & EvolutionPeer-reviewed
Dietary adaptation of FADS genes in Europe varied across time and geography
Kaixiong Ye, Feng Gao, David Wang…·Alon Keinan
The paper shows that positive selection on FADS genes in Europe occurred before and after farming, with geographic variation and associations with lipid levels and disease risk.
89 citationstop 2% - Evolutionary BiologybioRxiv
Positive selection on a regulatory insertion-deletion polymorphism in FADS2 influences apparent endogenous synthesis of arachidonic acid
Kumar S.D. Kothapalli, Kaixiong Ye, Maithili S. Gadgil…·J. Thomas Brenna
The paper identifies a regulatory insertion-deletion polymorphism in FADS2 associated with increased arachidonic acid synthesis in individuals with a plant-based diet.
DOI 10.1093/molbev/msw049