Alon Keinan

Dietary adaptation of FADS genes in Europe varied across time and geography

The paper shows that positive selection on FADS genes in Europe occurred before and after farming, with geographic variation and associations with lipid levels and disease risk.

Positive selection on a regulatory insertion-deletion polymorphism in FADS2 influences apparent endogenous synthesis of arachidonic acid

The paper identifies a regulatory insertion-deletion polymorphism in FADS2 associated with increased arachidonic acid synthesis in individuals with a plant-based diet.

The genetics of Bene Israel from India reveals both substantial Jewish and Indian ancestry

This study analyzes the genetic ancestry of the Bene Israel community, revealing substantial Jewish and Indian admixture with a sex-biased contribution and recent population bottleneck.

XWAS: a software toolset for genetic data analysis and association studies of the X chromosome

XWAS provides tools for X chromosome analysis in GWAS, identifying new genetic associations in immune disorders and coronary artery disease risk factors.

Inference of super-exponential human population growth via efficient computation of the site frequency spectrum for generalized models

This study develops a method to efficiently compute the site frequency spectrum under generalized population growth models and applies it to show human population growth faster than exponential.

Accounting for eXentricities: Analysis of the X chromosome in GWAS reveals X-linked genes implicated in autoimmune diseases

The paper analyzes the X chromosome in GWAS to identify X-linked genes associated with autoimmune diseases, finding several genes linked to conditions like Crohn's disease and ulcerative colitis.