Prognostically favorable immune responses to ovarian cancer are distinguished by self-reactive intra-epithelial plasma cells
Allyson C. Banville, Céline M. Laumont, Karanvir Singh, Breeze Gladwin, Jaden Dedora, Liam Mitchell, Jen Chin C. Wang, Alex Miranda, Bridget Mateyko, Elizabeth A. Chavez, Gian Luca Negri, Shuangshuang Cheng, Julian Smazynski, Katy Milne, Kylee Wright, , Brad H. Nelson
The paper identifies self-reactive intra-epithelial plasma cells in ovarian cancer that correlate with improved prognosis and suggest a mechanism for immune response against tumor heterogeneity.
bioRxiv · May 12, 2025 · PreprintCancer Biology