Maternal type 2 immunity promotes a microchimeric transfer of systemic type 2 immunity to offspring.
Malika Gabier, Matthew Darby, Alisha Chetty, A'ishah Taliep, Peter C. Cook, Bernhard Ryffel, Benjamin G Dewals, Menno J. Oudhoff, Adam F. Cunningham, Emer Hickey, William G. C. Horsnell
This study shows maternal type 2 immunity, independent of antigen exposure, transfers protective immunity to offspring via microchimeric cells.
bioRxiv · Jan 3, 2025 · PreprintImmunology