Author

Peter C. Cook

University of ExeterORCID 0000-0002-5208-4985Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Andrew S. MacDonaldiD· 2 shared Stefano A. P. ColomboiD· 2 shared A'ishah Taliep· 1 shared Adam F. CunninghamiD· 1 shared Alisha ChettyiD· 1 shared Amanda J. L. RidleyiD· 1 shared Ana Cruz· 1 shared Angela SimpsoniD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

Andrew S. MacDonaldORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mgl2+ cDC2 triggering of fungal allergic inflammation depends on a spore induced glycolytic shift fuelled by local availability of glucose

Julio Furlong-Silva, George Vere, Phuong Tuyen Nguyen, Nigel Gotts, Yun Xu A, Stefano A. P. Colombo, Daniel P. Conn, Bethany L. McCann, Ana Cruz, Laila Alsharq, Craig Beall, Rafael José Argüello, Shizuo Akira, Selinda J. Orr, Salomé LeibundGut‐Landmann, , Peter C. Cook

This study shows that Mgl2+ cDC2s trigger fungal allergic inflammation through a glycolytic shift driven by glucose availability after spore uptake.

bioRxiv · Jul 13, 2025 · PreprintImmunology

Hallmarks and metabolic regulation of type 2 activated human lung macrophages

Amanda J. L. Ridley, Annabel J. Curle, Stefano A. P. Colombo, Joshua J. Hughes, Douglas P. Dyer, Angela Simpson, Maria B. Feeney, Peter C. Cook, Andrew S. MacDonald

This study identifies hallmark gene expression and metabolic profiles of type 2 activated human lung macrophages using primary tissue-derived cells.

bioRxiv · Feb 26, 2025 · PreprintImmunology

Maternal type 2 immunity promotes a microchimeric transfer of systemic type 2 immunity to offspring.

Malika Gabier, Matthew Darby, Alisha Chetty, A'ishah Taliep, Peter C. Cook, Bernhard Ryffel, Benjamin G Dewals, Menno J. Oudhoff, Adam F. Cunningham, Emer Hickey, William G. C. Horsnell

This study shows maternal type 2 immunity, independent of antigen exposure, transfers protective immunity to offspring via microchimeric cells.

bioRxiv · Jan 3, 2025 · PreprintImmunology