Author

Man-Tzu Wang

UPMC Hillman Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Arjun PennathuriD· 1 shared Ling DingiD· 1 shared Luping CheniD· 1 shared Shenyu Sun· 1 shared Shou‐Jiang GaoiD· 1 shared Suet Kee LooiD· 1 shared Tingting LiiD· 1 shared Xian WangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Arjun PennathurORCID

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1 paper

Recent·Most cited

CASTOR1: A Novel Tumor Suppressor Linking mTORC1 and KRAS Pathways in Tumorigenesis and Resistance to KRAS-Targeted Therapies in Non-Small Cell Lung Cancer

Xian Wang, Ling Ding, Shenyu Sun, Suet Kee Loo, Luping Chen, Tingting Li, Man-Tzu Wang, Arjun Pennathur, Yufei Huang, Shou‐Jiang Gao

This study identifies CASTOR1 as a tumor suppressor in NSCLC that modulates mTORC1 and KRAS signaling, and shows that its loss promotes tumorigenesis and resistance to KRAS inhibitors.

bioRxiv · Apr 23, 2025 · PreprintCancer Biology