Wen Wang

CMS improves sequencing uniformity and accuracy in non-canonical genomic regions by optimizing chemistry and enzymatic systems, reducing low-coverage bins and false negatives.

The paper analyzes single-cell RNA sequencing data to show that lung development involves regulatory changes and new genes, with some features specific to bony fishes and mammals.

Chromosome-scale inshore hagfish genome places 1R before the cyclostome-gnathostome split and 2R in the gnathostome stem, and reveals two cyclostome-specific duplications (CR1, CR2).

This study uses rare variant linkage analysis and long-read sequencing to identify a pathogenic FSHD1 allele in a family, mapping the disease locus to chromosome 4q35.2.

The paper identifies ruminant-specific conserved non-coding elements and develops a method to interpret their regulatory roles in rumen development using gene regulatory networks.

The paper analyzes 630 aquatic vertebrate genomes to create a compendium, revealing TE diversity and gene family evolution related to the water-to-land transition.

The paper identifies and characterizes unknown porcine protein isoforms using tissue-based proteome maps and improves genome annotation.

CIGAR-seq identifies mRNA modification regulators through CRISPR screening and RNA modification readout, revealing NSUN6 as a novel m5C methyltransferase.

The paper presents sequencing data from the GenoCare 1600 platform, demonstrating high accuracy and clinical applicability for microbial and viral samples.

The paper announces the Fish10K project to sequence 10,000 fish genomes and describes a workflow for biospecimen procurement, sequencing, and assembly.

This study identifies introgression and selection events in goat domestication, linking them to immune and behavioral genes.

The paper presents the first high-quality reference genome of the reindeer, providing insights into its evolution and unique biological features.