BioinformaticsbioRxivPreprint
A-LAVA: Detecting impact of germline variants on metabolic pathways in cancer genomes
Mansoureh Jalilkhany, Kiana Gallagher, Isabella Wehner…·Ibrahim Numanagić
A-LAVA identifies germline variants affecting metabolic pathways in cancer genomes through SNP, gene, and pathway-level analysis, improving accuracy by correcting for overlapping gene sets and reducing false positives.
DOI 10.1101/2025.08.30.673276