Author

Sarah J. McPhedran

BC Cancer Agency

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:GWAS summary statistics· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Julian J. LumiD· 2 shared Sarah MacPhersoniD· 2 shared Farouk S. NathooiD· 1 shared Gillian A. CarletoniD· 1 shared Ibrahim NumanagićiD· 1 shared Isabella Wehner· 1 shared Kiana Gallagher· 1 shared Leonardo Castro· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Julian J. LumORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 25, 2026

PRDX1 regulates T cell effector function in the ovarian tumor microenvironment

Sarah J. McPhedran, Gillian A. Carleton, Scott Hannan…·Julian J. Lum

This study identifies PRDX1 as a negative regulator of T cell effector function in the ovarian tumor microenvironment, showing its impact on cytokine production, metabolism, and viability.

DOI 10.64898/2026.08.21.746361

humanbulk RNA-seq

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BioinformaticsbioRxivPreprintAug 30, 2025

A-LAVA: Detecting impact of germline variants on metabolic pathways in cancer genomes

Mansoureh Jalilkhany, Kiana Gallagher, Isabella Wehner…·Ibrahim Numanagić

A-LAVA identifies germline variants affecting metabolic pathways in cancer genomes through SNP, gene, and pathway-level analysis, improving accuracy by correcting for overlapping gene sets and reducing false positives.

DOI 10.1101/2025.08.30.673276

humanGWAS summary statistics

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