Author

Manuel Saiselet

Université Libre de Bruxelles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Joel Rodrigues VitóriaiD· 2 shared Vincent DetoursiD· 2 shared Adrien TourneuriD· 1 shared Akeila BellahcèneiD· 1 shared Alex SpinetteiD· 1 shared Carine Maenhaut· 1 shared Christelle BouchartiD· 1 shared Denis LarsimontiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Joel Rodrigues VitóriaORCID

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2 papers

Recent·Most cited

Glycation Stress-Driven Transcriptomic Signature Predicts Survival Benefit from Adjuvant Gemcitabine in Resectable Pancreatic Cancer.

Oier Azurmendi Senar, Kosta Stosic, Christelle Bouchart, Julie Navez, Jawad Tarfouss, Rebekah Crake, Laurine Verset, Pieter Demetter, Marjorie Mauduit, Thierry Conroy, Jerome F. Cros, Rémy Nicolle, Manuel Saiselet, Joel Rodrigues Vitória, Vincent Detours, , Jean-Luc Van-Laethem

The paper develops a 16-gene signature (MG-GEM) that predicts survival benefit from adjuvant gemcitabine in resectable pancreatic cancer based on glycation stress, outperforming existing signatures.

bioRxiv · Jul 7, 2025 · PreprintCancer Biology

Transcriptional output, cell types densities and normalization in spatial transcriptomics

Manuel Saiselet, Joel Rodrigues Vitória, Adrien Tourneur, Ligia Craciun, Alex Spinette, Denis Larsimont, Guy Andry, Joakim Lundeberg, Carine Maenhaut, Vincent Detours

The paper shows that total read counts in spatial transcriptomics spots reflect cell numbers and biology, and that normalization by total read counts can distort cell-type-related expression.

Journal of Molecular Cell Biology · Jun 15, 2020Peer-reviewedGenomics