Experimental analysis of exome-scale mutational signature of glycidamide, the reactive metabolite of acrylamide
Maria Zhivagui, Alvin Wei Tian Ng, Maude Ardin, Mona I. Churchwell, Manuraj Pandey, Claire Renard, Stéphanie Villar, Vincent Cahais, Alexis Robitaille, Liacine Bouaoun, Adriana Heguy, Kathryn Z. Guyton, Martha R. Stampfer, James McKay, Monica C. Hollstein, , Jiří Zavadil
The paper identifies a unique mutational signature of glycidamide, a metabolite of acrylamide, through experimental and computational analysis, linking it to cancer genome patterns.
Genome Research · Apr 1, 2019Peer-reviewedGenomics