Functional identification of cis-regulatory long noncoding RNAs at controlled false-discovery rates
Bhavya Dhaka, Marc Zimmerli, Daniel Hanhart, Mario B Moser, Hugo Guillen-Ramirez, Sanat Mishra, Roberta Esposito, Taisia Polidori, Maro Widmer, Raquel García-Pérez, Marianna Kruithof‐de Julio, Dmitri Davidovich Pervouchine, Marta Melé, Panagiotis Chouvardas, Rory Johnson
The paper introduces TransCistor, a framework to identify cis-regulatory lncRNAs with controlled false discovery rates, finding that only a minority of lncRNAs are cis-acting, primarily as activators.
Nucleic Acids Research · Jan 26, 2024Peer-reviewedGenomics