Author
University of Bern
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Bhavya Dhaka, Marc Zimmerli, Daniel Hanhart…·Rory Johnson
The paper introduces TransCistor, a framework to identify cis-regulatory lncRNAs with controlled false discovery rates, finding that only a minority of lncRNAs are cis-acting, primarily as activators.
Roberta Esposito, Andrés Lanzós, Tina Uroda…·Rory Johnson
The paper identifies mutated long noncoding RNAs (lncRNAs) as contributors to tumour cell fitness through experimental validation of their oncogenic effects.
Roberta Esposito, Taisia Polidori, Dominik F. Meise…·Rory Johnson
The paper identifies 60 high-confidence oncogenic lncRNAs in NSCLC using CRISPR deletion screens and ASO validation, revealing therapeutic vulnerabilities.
Joana Carlevaro-Fita, Taisia Polidori, Monalisa Das…·Rory Johnson
The paper identifies TE fragments associated with lncRNA nuclear enrichment and shows their role in subcellular localization.
Carlos Pulido-Quetglas, Estel Aparicio-Prat, Carme Arnan…·Rory Johnson
CRISPETa is a scalable bioinformatic pipeline for designing paired CRISPR guide RNAs for genomic deletion, achieving ≥50% deletion efficiency in tested cases.