Fallopian tube precursor lesions of serous ovarian carcinoma require L1CAM for dissemination and metastasis
Kai Doberstein, Rebecca Spivak, Yi Feng, Sarah Stuckelberger, Gordon B Mills, Kyle M Devins, Lauren E Schwartz, Marcin P Iwanicki, Mina Fogel, Peter Altevogt, Ronny Drapkin
This study shows that L1CAM is essential for transformed fallopian tube secretory cells to detach, survive, and colonize the ovary in high-grade serous ovarian carcinoma.
bioRxiv · Mar 2, 2018 · PreprintCancer Biology