Author

Maria Cristina Sousa

University of Bern

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Approach:experimental assay· 1

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Alexandre LeitãoiD· 1 shared Andrew Frederick HemphilliD· 1 shared Anne‐Christine UldryiD· 1 shared Joachim MülleriD· 1 shared Kai Pascal Alexander HänggeliiD· 1 shared Kayode K. OjoiD· 1 shared Luis Miguel Ortega‐MoraiD· 1 shared Manfred HelleriD· 1 shared

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1 paper

Recent·Most cited

Systems BiologybioRxivPreprintOct 22, 2025

Bumped kinase inhibitor BKI-1708 interferes in cytokinesis and drives baryzoite stage conversion in the cyst-forming apicomplexan parasites Toxoplasma gondii, Neospora caninum and Besnoitia besnoiti

Maria Cristina Sousa, Joachim Müller, Kai Pascal Alexander Hänggeli…·Andrew Frederick Hemphill

This study shows that BKI-1708 induces baryzoite formation in T. gondii, N. caninum, and B. besnoiti, which exhibit distinct phenotypic and proteomic features and lack complete cytokinesis.

DOI 10.1101/2025.10.22.684074

experimental assay

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