Accurate transcription start sites enable mining for the cis-regulatory determinants of tissue specific gene expression
Mitra Ansariola, Valerie N. Fraser, Sergei A. Filichkin, Maria G. Ivanchenko, Zachary A. Bright, Russell A. Gould, Olivia R. Ozguc, Shawn T. O’Neil, Molly S. Megraw
The paper identifies cis-regulatory determinants of tissue-specific gene expression in Arabidopsis thaliana by analyzing TSS-seq, OC-seq, and RNA-seq data, finding that TSS-proximal TF binding sites are more important than distal chromatin regions.
bioRxiv · Sep 1, 2020 · PreprintGenomics