The PST repeat region of MDC1 is a tunable multivalent chromatin tethering domain
Joshua R. Heyza, Maria Mikhova, Gloria I. Perez, David G. Broadbent, Jens C. Schmidt
This study shows the PST repeat region of MDC1 is a multivalent chromatin tethering domain with tunable affinity that aids in DNA break tethering during HR and mitosis.
bioRxiv · Jan 10, 2025 · PreprintCell Biology