Functional Biosynthetic Stereodivergence in a Gene Cluster via a Dihydrosydnone N-oxide
Jiajun Ren, Anugraha Mathew, Maria Rodriguez Garcia, Tobias Kohler, Olivier Blacque, Anthony Linden, Leo Eberl, Simon Sieber, Karl Gademann
The paper investigates a gene cluster that produces both enantiomerically pure and racemic metabolites through a stereodivergent pathway involving a dihydrosydnone N-oxide intermediate.
Communications Chemistry · Dec 19, 2024Peer-reviewedBiochemistry