Serial synapse formation through filopodial competition for synaptic seeding factors
Mehmet Neset Özel, Abhishek Kulkarni, Amr Hasan, Josephine Brummer, Marian Moldenhauer, Ilsa-Maria Daumann, Heike Wolfenberg, Vincent J. Dercksen, Ferdi Rıdvan Kiral, Martin Weiser, Steffen Prohaska, Max von Kleist, P. Robin Hiesinger
The paper develops a 4D analysis method and computational model to show that filopodia compete for synaptic seeding factors, leading to serial synapse formation in Drosophila R7 photoreceptor axons.
Developmental Cell · Jul 25, 2019Peer-reviewedNeuroscience