Author

Mariana Witmer

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:plant (other)· 2 Approach:statistical model· 1

Frequent Co-Authors

Axel PouletiD· 2 shared Josien C. van WolfswinkeliD· 2 shared Danyan LiiD· 1 shared Hae-Lim LeeiD· 1 shared Karina AscunceiD· 1 shared Levi Cruz· 1 shared Romane S. CatheliniD· 1 shared Sudheesh Allikka ParambiliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

Axel PouletORCID

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2 papers

Recent·Most cited

Systemic RNAi in planarians depends on spread of RNPs from active stem cells

Sudheesh Allikka Parambil, Karina Ascunce, Axel Poulet, Levi Cruz, Hae-Lim Lee, Mariana Witmer, Josien C. van Wolfswinkel

This study investigates systemic RNAi in planarians, finding that it relies on active stem cells and Argonaute-siRNA complexes, without RNA amplification or transgenerational effects.

bioRxiv · Mar 4, 2026 · PreprintMolecular Biology

Two tiers of piRNA clusters balance diversification of piRNAs with limitation of off-target effects

Axel Poulet, Mariana Witmer, Danyan Li, Romane S. Cathelin, Josien C. van Wolfswinkel

The paper identifies two types of piRNA clusters in planarians, Seed and Spread clusters, which balance piRNA diversity with off-target effect limitation through distinct mechanisms.

bioRxiv · Jan 31, 2026 · PreprintMolecular Biology