Molecular BiologybioRxivPreprint
Two tiers of piRNA clusters balance diversification of piRNAs with limitation of off-target effects
Axel Poulet, Mariana Witmer, Danyan Li…·Josien C. van Wolfswinkel
The paper identifies two types of piRNA clusters in planarians, Seed and Spread clusters, which balance piRNA diversity with off-target effect limitation through distinct mechanisms.
DOI 10.64898/2026.01.28.702291