Josien C. van Wolfswinkel

This study investigates systemic RNAi in planarians, finding that it relies on active stem cells and Argonaute-siRNA complexes, without RNA amplification or transgenerational effects.

The paper identifies two types of piRNA clusters in planarians, Seed and Spread clusters, which balance piRNA diversity with off-target effect limitation through distinct mechanisms.

This study shows that H3.1K27M disrupts chromatin maturation, leading to TSK/TONSL activation and genomic instability in Arabidopsis.

NODeJ is an ImageJ plugin that automates 3D segmentation of nuclear objects, improving efficiency and reducing bias in analyzing chromatin organization.