The malaria parasite PP1 phosphatase controls the initiation of the egress pathway of asexual blood-stages by regulating the rounding-up of the vacuole
Marie Seveno, Manon N. Loubens, Laurence Berry, Arnault Graindorge, Maryse Lebrun, Catherine Lavazec, Mauld H. Lamarque
This study identifies PP1 phosphatase as a dual regulator of the malaria parasite's egress pathway, controlling cGMP homeostasis and vacuole rounding-up.
PLoS Pathogens · Jan 14, 2025Peer-reviewedMicrobiology