Manon Loubens

A structure-based epitope tagging approach identifies vulnerable sites on the malarial P36-P52 protein complex for antibody-mediated neutralization of Plasmodium sporozoites

The paper identifies vulnerable sites on the P36-P52 protein complex of Plasmodium sporozoites using structural biology and functional assays, showing that antibodies targeting these sites can neutralize SPZ invasion.

The malaria parasite PP1 phosphatase controls the initiation of the egress pathway of asexual blood-stages by regulating the rounding-up of the vacuole

This study identifies PP1 phosphatase as a dual regulator of the malaria parasite's egress pathway, controlling cGMP homeostasis and vacuole rounding-up.