Daughterless, the Drosophila orthologue of TCF4, is required for associative learning and maintenance of synaptic proteome
Laura Tamberg, Mariliis Jaago, Kristi Säälik, Alex Sirp, Jürgen Tuvikene, Anastassia Shubina, Carl Sander Kiir, Kaja Nurm, Mari Sepp, Tõnis Timmusk, Mari Palgi
This study shows that the Drosophila orthologue of TCF4, Daughterless, is essential for associative learning and synaptic protein maintenance, with implications for modeling human intellectual disabilities.
Disease Models & Mechanisms · Jul 1, 2020Peer-reviewedNeuroscience