Author

Mario P Tschan

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Kristina Seiler· 1 shared Magali Humbert· 1 shared Severin Mosimann· 1 shared Sharon L McKenna· 1 shared Vreni Rentsch· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

Kristina Seiler

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1 paper

Recent·Most cited

Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy

Magali Humbert, Kristina Seiler, Severin Mosimann, Vreni Rentsch, Sharon L McKenna, Mario P Tschan

This study shows that reducing FASN expression enhances AML cells' response to differentiation therapy by promoting lysosomal biogenesis and TFEB activation.

bioRxiv · Jan 29, 2020Cancer Biology